Healthy Life Style

PD is characterized by fibrosis of the tunica albuginea secondary to aberrant wound healing. Typically, no predisposing trauma is recollected by the patient. However, biochemical examination of acutely diseased tunical tissue shows a typical cascade of wound-healing pathways leading to eventual fibrosis. This process can be subdivided into the acute proliferative phase and subsequent remodeling phase characterized by maturation of fibrosis and scar formation. The cascade begins with exposure of platelets to collagen, thus activating the coagulation cascade and leading to the release of potent chemoattractant molecules, such as transforming growth factor beta (TGF-beta), platelet-derived growth factor (PDGF), tumor necrosis factor alpha (TNF-alpha), and interleukin-1 (IL-1). Fibrin is deposited to act as a matrix for subsequent repair. Inflammatory cells, beginning with neutrophils and followed by macrophages, infiltrate the area. These cells not only perpetuate the inflammatory signaling cascade but also stimulate the release of growth factors, such as vascular endothelial growth factor (VEGF). The proliferative phase involves the influx of fibroblasts and deposition of collagen types I and III. The remodeling phase involves the tightly regulated interaction of profibrotic and antifibrotic substances, such as matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs), that are responsible for final scar formation. Recent research into the etiology of PD implies an imbalance between profibrotic and antifibrotic substances. Overexpression of TGF-beta1 has been shown to induce penile plaques in the rat model. TGF-beta1 has also been shown to be overexpressed in PD plaques as compared with patients without evidence of PD. Another group of profibrotic proteins includes fibrin and plasminogen activator inhibitor-1 (PAI-1). Like TGF-beta1, fibrin has been shown to induce plaque formation in an animal model; levels of PAI-1 are elevated in Read More This Post...

Tantra is a loose term assigned to practices characterized by ritual, rites of passage, energy work, and the utilization of the mundane to reach the supramundane and understanding the relationship between the micro and macrocosm. These aspects of Tantra can be spiritual and/or material. A guru is often consulted to help the practitioner have a mystical experience and properly guide them through the associated rituals. Yoga is a vital part of Tantra as it awakens the ability to reach the divine in the practitioner. An integral part also of Buddhism, there is different forms of yoga in existence to meet a person’s spiritual needs - varying from vigorous to peaceful movements. Visualizations, evocations and mantras can also help the Tantra practitioner reach a point of spiritual awareness. Tantra has had roots in areas of the world such as China, Tibet, Japan, Cambodia and Indonesia. It is closely affiliated with religions like Hinduism, Buddhism and Jainism. In Hinduism, Tantra ties closely to Vedic tradition- or rather the rejection of the orthodox beliefs. Practicing Tantra is meant to bring the practitioner a blissful feeling of self awareness while sorting away illusions. The exact rituals associated with Tantra are difficult to pin down since they vary greatly depending on region and the available tantric community. Commonly employed rituals include the repetition of mantras and yantras (amulets) to invoke deities. Feasts and bodily functions can also be included in the rituals. Although it gets the most attention, sexual rituals play a very small part of traditional tantric practices. The term Tantra is of course most familiar to Westerners for the sexuality related to that small portion of rites. It is believed the sexual practices originated early in the Hindu culture as a means of forming body fluids that were thought to be transformative and a necessary offering to the deities of the Tantra. The fluid exchange often involved man, woman and guru Read More This Post...

There are five essential skin types: normal, dry, oily, combination and sensitive. Before buying your makeup, toiletries and other cosmetic products for skin care, do make sure that it goes well with your skin type. How to identify normal skin? It is soft textured and evenly toned with minuscule pores. This skin type has a reasonable oil and water content and gives you smooth and soft feeling. The color of the skin shines below the translucent face. This skin type definitely needs care if it is to last. All you need to do is regular toning, cleansing, and moisturizing to maintain its texture and feel for long. How to identify dry skin? This skin type requires both sebum and moisture. It looks fine textured, patchy, transparent and weak. This type of skin flakes and chaps simply compared to other skin types. Minuscule expression lines may be obvious. Signs of a dry skin are: a) Blistering patches that vanish with regular moisturizing. b) Finely textured with the minute openings not being observable. c) Small expression lines that do not disappear. d) The skin of neck and cheeks seems sinister. Keep away from harsh soaps to stop loss of natural oils and exposure to sun and air-conditioners which rob the water part of the skin. How to identify oily skin? This type of skin has over hasty sebaceous (oil-producing) glands, which formulates the face glossy particularly down the central panel-of your nose, forehead and chin. The pores of this skin type are puffy making it prone to black-head, spot and acne. Oily skin needs special cleansing to stay the pores unclogged. Women with oily skin require adopting a daily proper process of cleansing to stop accumulation of dirt on the skin surface. How to identify combination skin? This skin type is generally very general and necessitates separate cure for each area. It is oily down the central panel and parched on the cheeks. The forehead, nose and chin require additional attention as they may be prone to clusters of blackheads Read More This Post...

Sex-positive feminism is also called pro-sex feminism, sex-radical feminism or sexually liberal feminism. The sex-positive feminist movement was started in the early 1980’s and was set up in response to anti-pornography feminist. Advocates of the sex- positive movement are Ellen Willis, Susie Bright, Patrick Califia and Gail Rubin. Catharine Mackinnon, Andrea Dworkin, Robin Morgan and Dorchen Leidholdt were prominent anti-pornography feminists. They believe that pornography is an example of oppression of women, which is opposite to what the sex-positive feminist believe. Thus creating the beginning of the “Feminist Sex Wars” in the early 1980’s. Gayle Rubin an acclaimed sex-positive feminist purports: “There have been two strains of feminist thought on the subject. One tendency has critized the restrictions on women’s sexual behaviour and denounced the high costs imposed on women for being sexually active. “This tradition of feminist sexual thought has called for liberation that would work for women as well as for men. The second tendency has considered sexual liberalization to be inherently a mere extension of male privilege. This tradition resonates with conservative, anti-sexual discourse.” However some sex-positive feminists are not against other feminists but are attacking the patriarchal control of women’s sexuality. They also purport: ” that in the area of sexuality, government blatantly discriminate against women.” The ideology behind sex-positive feminism is sexual freedom of women is essential. They will fight any legislation or social efforts to control individual’s sexual activity. Sex-positive feminist will fight the government or other feminist who they see as trying to control people’s sexuality. They believe that as long as it between two consenting adults it is no-one business what you do in your sex life. Sex-positive feminist are not only for women they support sexual Read More This Post...

Erectile dysfunction is a condition that inhibits the erection function of a man’s penis. It can be caused by emotional problems, circulatory problems and by physical injuries to the penis or groin. While most of these problems can be corrected with medication or surgery, failing to treat ED can damage more than your health, it can also damage your relationship with your mate. In the past, emotional problems have been blamed for the majority of erectile dysfunction cases. However, recent studies have shown that this is not the case. In reality, physical problems seem to be the main cause of most cases of ED. Unfortunately there are a lot of different physical conditions that can lead to erectile dysfunction. Serious health conditions like diabetes and heart disease can lead to erectile dysfunction, and are top causes of this condition. The reason that these health conditions can lead to erectile dysfunction is because they impact your circulatory system, which in turn impacts the amount of blood that is able to reach your penis and support an erection. These diseases can also damage the nerves required to establish and sustain an erection. When these conditions are not treated properly, and in some cases, even when they are treated appropriate, ED can develop. Hormone disorders can also lead to erectile dysfunction, however, less than 5 percent of ED cases are caused by this. Low levels of testosterone or excessively high levels of prolactin can both impact a man’s libido and impair his ability to achieve an erection. Physical trauma can also lead to erectile dysfunction. Trauma to the pelvis, spinal injury and lower organs, can all lead to damage of vital nerves and blood vessels required for erections. Abdominal and lower gastrointestinal surgeries are particularly high risk activities that can easily lead to ED problems. Fortunately, new surgical technologies are making these types of surgeries much safer for men. Drugs can also lead to erectile Read More This Post...